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TEST SUBMISSION
Description
This template shows the three steps of leukocyte extravasation, chemoattraction, tethering and rolling, and migration, as a leukocyte moves along the vessel wall and squeezes through the endothelium toward a site of inflammation marked by chemokines. An inset panel details the selectin and glycan interactions, including sialyl Lewis X epitope binding to E- or P-selectin and L-selectin, that mediate leukocyte and lymphocyte adhesion to the endothelial cell.
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