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Tetracycline (Tet) Regulation System
Description
This template compares the Tet-off and Tet-on tetracycline regulation systems, showing the tTA and rtTA cassettes and how doxycycline binding either releases the transactivator to silence gene expression or activates it to induce gene expression at the TRE-controlled promoter. Arrows and color-coded proteins trace the shift between active and reduced gene expression before and after doxycycline addition in each system.
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