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BioRender Template
Epithelial-Mesenchymal Plasticity (EMP) and Fitness
Creator
s
Description
Gaining EMP lets cells adapt by adopting epithelial or mesenchymal traits. A) Mesenchymal traits help tumor cells invade by degrading the basement membrane. B) Hybrid E/M cells with stemness excel at metastatic seeding. C) Epithelial traits promote metastatic outgrowth via proliferation. D) Mesenchymal cells survive chemotherapy through dormancy or ABC transporter upregulation. Adapted from Fig. 2, Proactive and reactive roles of TGF-β in cancer.
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