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BioRender Template
The Inhibition of Ribosomal Translocation by Antibiotic Lariocidin
Creator
s
Description
This figure demonstrates how the antibiotic lariocidin inhibits bacterial protein synthesis by inhibiting the process of translocation. Lariocidin binds the 30S subunit at a distinct site adjacent to the ribosome's decoding site, preventing the conformational changes required to allow translocation along the mRNA. Lariocidin-bound ribosomes are usually arrested at the start codon of the mRNA.
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