BioRender Template
The Ischemic Cascade
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Description:
The ischemic cascade graph represents the sequence of events that occur in the brain during an ischemic stroke.
Excitotoxicity: excessive activation of glutamate receptors leads to the overstimulation of neurons, causing cell damage and death.
Oxidative stress: increase in reactive oxygen species (ROS) production can damage cellular membranes, proteins and DNA.
Inflammatory response: release of pro-inflammatory cytokines and chemokines, attracting immune cells to the affected area.
Updated
August 2026
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The ischemic cascade graph represents the sequence of events that occur in the brain during an ischemic stroke.
Excitotoxicity: excessive activation of glutamate receptors leads to the overstimulation of neurons, causing cell damage and death.
Oxidative stress: increase in reactive oxygen species (ROS) production can damage cellular membranes, proteins and DNA.
Inflammatory response: release of pro-inflammatory cytokines and chemokines, attracting immune cells to the affected area.