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The physiological basis of the fMRI BOLD response

An editable high resolution scientific image depicting The physiological basis of the fMRI BOLD response

Description

A complex interplay of events that lead to the generation of the BOLD signal, elicited by a stimulus. This induces a complex cascade of processes which are part of the neurovascular coupling signaling. That produces a haemodynamic response that is influenced by multiple factors that modify the [oxyHb]:[deoxyHb] ratio, resulting in changes in the inhomogeneity in the magnetic field, detected as a T2*-weighted signal by the MRI scanner, representing the functional MRI BOLD response.
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