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The roles and mechanisms of LEC–A2AR in skin lymphangiogenesis during salt-induced hypertension
Description
This template has unveiled the essential mechanisms by which the A2AR modulates blood pressure homeostasis, highlighting the intricate interplay between molecular signaling pathways and physiological regulation. The modulation of lymphatic endothelial A2AR-mediated signaling, which activates the vascular endothelial growth factor receptor 2 (VEGFR2) in a vascular endothelial growth factor (VEGF)-independent manner, plays a crucial role in regulating dermal lymphangiogenesis and sodium balance.
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