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The Zinc importation systems present in P. aeruginosa

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Josephine Goodall
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Description: In addition to the ZnuABCD system found in many gram-negative bacteria P. aeruginosa has several other putative Zn2+ import systems. PA2911-PA2914 and PA4063-PA4066 both share similarities with ZnuABCD, with PA2911-PA2914 is predicted to interact with chelated forms of Zn2+ and PA4063-PA4066 has two potential periplasmic SBP type proteins. HmtA is a P-type ATPase which exclusively transports Zn and Cu from the periplasm to the cytoplasm. Figure adapted from a figure in V. Ducret, et al. (2022)

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In addition to the ZnuABCD system found in many gram-negative bacteria P. aeruginosa has several other putative Zn2+ import systems. PA2911-PA2914 and PA4063-PA4066 both share similarities with ZnuABCD, with PA2911-PA2914 is predicted to interact with chelated forms of Zn2+ and PA4063-PA4066 has two potential periplasmic SBP type proteins. HmtA is a P-type ATPase which exclusively transports Zn and Cu from the periplasm to the cytoplasm. Figure adapted from a figure in V. Ducret, et al. (2022)

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