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Three Major MAP Kinase Pathways: ERK, JNK, p38
Description
This template maps the three major MAPK cascades activated downstream of a receptor and small GTPases (RAS, RAC, CDC42, RHO), showing how the ERK, JNK, and p38 branches are each phosphorylated through a series of kinases to activate transcription factors such as TCF/SRF, AP1, and ATF2. A side panel summarizes the generic membrane-to-transcription-factor phosphorylation cascade shared by all three pathways.
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