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Toll-Like receptor 4 signaling pathway: activation by binding of saturated fatty acids.
Creator
s
Description
Diet-induced obesity is associated with chronic low-grade inflammation in the hypothalamus, particularly involving the activation of the Toll-like receptor 4 (TLR4) pathway, which plays a crucial role in the inflammatory response. Activation of TLR4 by saturated fatty acids is a major trigger of obesity-related inflammation.
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