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Transgenerational inheritance of epigenetic disorders
Description
Transgenerational inheritance of epigenetic modifications are influenced by
hormonal fluctuations, environmental exposures, lifestyle factors, and maternal/paternal stressors that can be passed on to subsequent generations. Such epigenetic modifications alter the imprinting status of various genes manifesting in imprinting disorders including Prader-Willi, Angelman's and Beckwith-Wiedemann Syndromes affiliated with cellular growth abnormalities that predispose the individual to an array of cancers.
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