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Treatment of Urinary Tract Infections with D-Mannose
Description
This template compares a normal urinary tract infection, where E. coli use FimH-tipped pili to bind mannosylated uroplakin 1a on the bladder epithelium, to D-mannose treatment, where exogenous D-mannose competitively binds FimH and blocks bacterial adhesion. Labeled components include the type 1 pilus, mannose residue, GlcNAc, and uroplakin 1a on the epithelial cell.
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