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BioRender Template
Tumor Microenvironment and Metastasis
Creator
s
Description
Adhesion molecules and chemokines enable cancer cells to enter the bloodstream, transforming into circulating tumor cells (CTCs). The epithelial-mesenchymal transition (EMT) enhances CTCs' migratory properties. Traveling through the circulatory or lymphatic system, CTCs reach distant organs, where interactions with endothelial cells and chemokines guide their extravasation and colonization. This succinctly outlines the key steps in cancer metastasis.
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