BioRender Template
Type 1 Hypersensitivity Reaction
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Description:
On exposure to allergen, IgE antibody gets stimulated. Thereafter they bind to the Fc receptor of immune cells (e.g., mast cells, basophils etc.). The binding of IgE antibodies to the Fc receptors activate these cells- initiating a signaling cascade, which ultimately results into release of intracellular granules into blood through a process, termed as degranulation.
Updated
August 2026
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On exposure to allergen, IgE antibody gets stimulated. Thereafter they bind to the Fc receptor of immune cells (e.g., mast cells, basophils etc.). The binding of IgE antibodies to the Fc receptors activate these cells- initiating a signaling cascade, which ultimately results into release of intracellular granules into blood through a process, termed as degranulation.








