BioRender Template

UPR Signaling (ATF6, PERK, IRE1)

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Emma Madden

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BioRender Team

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Description: This template shows the three arms of the unfolded protein response in the endoplasmic reticulum: ATF6, PERK, and IRE1. Each sensor triggers a distinct downstream cascade, from ATF6 cleavage and eIF2 alpha phosphorylation to XBP1 splicing, that converges on the nucleus to regulate genes for ER chaperones, amino acid biosynthesis, and lipid synthesis.

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What does the UPR Signaling (ATF6, PERK, IRE1) template show?

This template shows the three arms of the unfolded protein response in the endoplasmic reticulum: ATF6, PERK, and IRE1. Each sensor triggers a distinct downstream cascade, from ATF6 cleavage and eIF2 alpha phosphorylation to XBP1 splicing, that converges on the nucleus to regulate genes for ER chaperones, amino acid biosynthesis, and lipid synthesis.

Is the UPR Signaling (ATF6, PERK, IRE1) template free to use?

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Can I edit or customize this template?

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