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BioRender Template
Vemurafenib in Oncogenic BRAF Signaling Pathway in Melanoma
Description
This template compares normal RAS-RAF-MEK-ERK signaling downstream of a growth factor receptor with oncogenic BRAF V600 signaling that drives constitutive cell proliferation and survival independent of extracellular signals. It also shows how the BRAF inhibitor vemurafenib selectively blocks BRAF V600 to arrest MEK and ERK activation and reduce proliferation.
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