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Virulence mechanism of Trypanosoma cruzi in the acute phase

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Eudes Simões

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Description: After penetration, metacyclic trypomastigote express proteins that are responsible for activating the phagocytosis; then antioxidative proteins start to be produced, opposing the intracellular mechanisms of destruction; the parasite then breaks the cell membrane and expresses a series of membrane glycoproteins that act to inhibit the different pathways of the complement.

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After penetration, metacyclic trypomastigote express proteins that are responsible for activating the phagocytosis; then antioxidative proteins start to be produced, opposing the intracellular mechanisms of destruction; the parasite then breaks the cell membrane and expresses a series of membrane glycoproteins that act to inhibit the different pathways of the complement.

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