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BioRender Template
X-Linked Alport Syndrome Pathology
Creator
s
Description
Pathological description of X-linked Alport Syndrome in humans and mice. Mutations on the Col4 gene (mainly the Col4a5 gene) prevent the synthesis of collagen IV, an integral component of the glomerular basement membrane. This results in the early onset of impaired renal function and an increased risk of premature kidney failure.
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